Homeotic selector gene

Homeotic selector genes confer segment identity in Drosophila. They encode homeodomain proteins which interact with Hox and other homeotic genes to initiate segment-specific gene regulation.[1][2]

An example of a homeotic selector gene is 'Deformed' (Dfd) which signals identity of a mandible.[3][4]

References

  1. ^ Alberts, Bruce (2002). Molecular biology of the cell. New York: Garland Science. ISBN 0-8153-3218-1. 
  2. ^ "Homeotic selector gene - definition from Biology-Online.org". 2009-01-08. http://www.biology-online.org/dictionary/Homeotic_selector_gene. Retrieved 2009-12-14. 
  3. ^ Kuziora MA, McGinnis W (November 1988). "Autoregulation of a Drosophila homeotic selector gene". Cell 55 (3): 477–85. doi:10.1016/0092-8674(88)90034-7. PMID 2902926. http://linkinghub.elsevier.com/retrieve/pii/0092-8674(88)90034-7. Retrieved 2011-05-07. 
  4. ^ McGinnis W, Jack T, Chadwick R et al. (1990). "Establishment and maintenance of position-specific expression of the Drosophila homeotic selector gene Deformed". Adv. Genet. 27: 363–402. PMID 1971987.